Epigenetics: Principles of Eukaryotic Genome Control

Sinopse

Epigenetics: Principles of Eukaryotic Genome Control provides an integration of classical and molecular genetic perspectives to highlight underlying principles of gene and genome control in eukaryotes, with an emphasis on relevance for human disease. Among epigenetic phenomena discussed in this thorough treatment are imprinting, X chromosome inactivation, and DNA methylation, with specific examples from model systems and clear explication of experimental methods. Key features include: * Provides a cutting edge review of the concepts, findings, and techniques in this exciting field * Highlights relationship to development of cancer and other human diseases throughout * Presents an extensive annotated bibliography * Written at a technical level suitable for anyone with an introductory knowledge of genetics and biochemistry * Integrates classical and molecular viewpoints * Summarizes major methods of molecular genetic analysis Epigenetics: Principles of Eukaryotic Genome Control is an indispensable addition to the bookshelf of any advanced undergraduate and graduate student in genetics, molecular biology, and biochemistry.  

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